Cryotherapy vs Laser for Plantar Warts: Which Works Best?
- Sondema Tarr
- 10 hours ago
- 3 min read

If you’ve been dealing with a plantar wart that just won't go away, you know how uncomfortable, or even painful, these can be—especially when every step reminds you it’s still there. Many people try freezing or over-the-counter treatments first, only to find that the wart keeps coming back.
Two of the most common professional treatments for plantar warts are cryotherapy and laser therapy. Both aim to remove the wart and stimulate healing—but they work in very different ways. Here’s how they compare, and how to know which might be right for you.
What Is Cryotherapy?

Cryotherapy uses liquid nitrogen to freeze the plantar wart , causing it to blister and eventually peel away. During the procedure, the skin is exposed to extreme cold for several seconds.
Most people feel an intense stinging or burning sensation, followed by some soreness and blistering over the next few days.
Cryotherapy can work for smaller, superficial plantar warts, but results vary—especially for severe cases of plantar warts. It usually requires three to six sessions, spaced a few weeks apart.
Pros of cryotherapy:
Widely available and more familiar to most patients
Lower upfront cost per session
Quick procedure time
Cons:
Can be painful during and after treatment
May cause blistering or scarring
Lower success rate on deep or stubborn plantar warts
What Is Laser Therapy?
Laser therapy uses concentrated light energy to target the blood vessels feeding the wart, cutting off its oxygen supply. This causes the wart tissue to naturally slough off over time while sparing healthy skin around it.
At Direct Podiatry Arizona, we use the Remy Class IV laser, a medical-grade system that precisely stimulates an immune response in the area of your foot affected by the wart, destroying the wart, without damaging the surrounding tissue.
Pros of laser treatment:
More precise and comfortable than freezing
Fewer sessions required
Helps stimulate your body’s natural healing response
Cons:
Slightly higher upfront cost compared to cryotherapy
Mild warmth during treatment
“Most patients describe laser therapy as a warm tingling feeling rather than pain. You can walk out of the office and continue your day as usual.”
Effectiveness: Laser vs Cryotherapy
Both treatments can work—but the success rate tends to be higher with laser therapy, especially for warts that have been around for a long time, or painful plantar warts.
Cryotherapy typically clears about 50–70% of warts, while laser treatment clears 70–90%, depending on the how deep the plantar wart is, and size of the plantar wart. Laser treatment also tends to lower the chance of the wart coming back.
Treatment | Typical Sessions | Discomfort | Downtime | Clearance Rate |
Cryotherapy | 3–6+ | Moderate | Blistering, soreness | 50–70% |
Laser | 1–3 | Mild warmth | Minimal | 70–90% |

Pain and Healing Time
Cryotherapy: Expect temporary blistering and soreness for several days. You may need to cover the area until healed.
Laser therapy: Mild redness or tenderness right after treatment, but most patients return to work or activity the same day.
For patients who’ve already tried cryotherapy and found it too painful or it just didn't work, laser therapy for plantar warts offers a comfortable and modern alternative.
Cost and Convenience
While cryotherapy can seem to be less per visit, the need for many sessions can add up. Laser therapy often gets your plantar wart to clear in fewer visits—saving you time and trips to the office.
At our Tempe office, laser wart treatments are quick, and require no downtime. You can walk in and walk out, ready to continue your day.
Which Treatment Is Right for You?
If you’ve had cryotherapy before without results that stuck—or simply want a more comfortable, modern solution—laser therapy may be the best choice.
Every patient’s skin and immune system responds differently, so an in-person evaluation, with an integrative podiatry focus, helps determine the right approach for you.
